Numerous approaches have been developed to define the humanitarian-development nexus and more broadly, the humanitarian-development-peace nexus. This report examines the humanitarian-development nexus and its application to health interventions in South Sudan, specifically family planning, reproductive health, and maternal, newborn, and child health (FP/RH/MNCH), concluding with recommendations for stakeholders related to health services, institutional architecture, leadership, financing, coordination, and localization.