This report captures results and analysis from interviews with Ghana Ministry of Health and Sanitation staff at the national, district, and facility levels to assess the successes of, challenges to, and opportunities for effective implementation of Integrated Management of Childhood Illness (IMCI), part of a multi-country study begun in 2022. Despite broad support for the IMCI protocol, implementation in Ghana has been limited, with four key challenges cited by multiple interviewees: 1) policy restriction on CHPS (Community Health Planning and Service) activities, 2) insufficient prioritization by international partners working in Ghana, 3) frequent stockouts of medicines essential for IMCI, and 4) lack of referral transport. The report provides key programmatic recommendations to address these barriers.