This report summarizes evidence about vaccine hesitancy trends for both COVID and non-COVID immunizations. It is a special investigation into the role of faith actors on immunization uptake in USAID priority countries for maternal, newborn, and child health and family planning/reproductive health. The report explores common themes in vaccine hesitancy relating to faith. The evidence concludes that vaccine hesitancy among faith communities threatens routine immunization coverage but also demonstrates the potential of engaging faith actors as partners to increase immunization coverage.