There has been a tremendous shift in recent years in how we understand humanitarian and development settings, and in turn, how we frame interventions in such contexts. Notions of a humanitarian-development divide, gap, or continuum go back decades and are outdated, as they have never fully depicted the overlapping reality and needs of most contexts across the world. Though numerous approaches have been developed to date, a broader understanding and operationalization within the humanitarian-development nexus (HDN) remains necessary, specifically in the health sector. Examining each of these approaches provides a foundation for how these may be translated to the health sector using an HDN lens. This landscape analysis and framework reviews existing frameworks, explores the HDN from a health perspective, and introduces a framework for maternal, newborn, and child health, family planning, and reproductive health (MNCH/FP/RH) in the HDN.