In 2020, the COVID-19 pandemic shocked health systems, demanding the urgent identification and prioritization of immediate healthcare facility needs. Beginning in August 2020, USAID’s MOMENTUM Country and Global Leadership provided rapid technical and capacity development assistance to local health networks in India and four other countries to improve facility readiness in water sanitation and hygiene (WASH) and infection prevention and control (IPC). This package of materials details the impact and outcomes of this work, as well as lessons learned to inform future WASH and IPC efforts in healthcare facilities and quality improvement programming.